"France's covid testing teams down tools – for summer holidays: Laboratory staff head off on vacation just as signs of a second wave strike leaving country struggling with demands for tests
Doctors have warned the vacation crunch is just part of a larger web of failures Strategy described by government's own virus advisory panel as 'insufficient' It comes as France, along with much of Europe, is seeing surge of Covid-19 cases"
"Erectile dysfunction drug aviptadil may also treat Covid-19, experts believe
Aviptadil has been fast-tracked into clinical trials in the US since June Early results show patients have come off ventilators in three to four days The drug is a synthetic form of a natural peptide in the body called VIP It's shown to prevent inflammation and stop replication of the virus in lung cells"
Glennkoks, hopefully you’ll take the time to read what follows and let me know if it makes sense.
The body is able to handle a small dose of any poison or infective agent.
A small amount of COVID-19 is not a problem. The body has a mechanism for replicating certain cells. Unfortunately, COVID-19 is able to use this system and a small dose of 1 cell can before long become billions of cells.
If one COVID-19 cell enters your body and infects you, you will never notice it. If it turns into billions of cells and they infect you, you can have a problem.
Zinc has been proven to be capable of stopping virus replication. But it has to get into the cells which are being hijacked by the virus into replicating the virus. HCQ helps zinc block the replication by allowing it to penetrate into cells.
If unimpeded, the COVID-19 multplication is very fast and within hours the infection begins. After a while your body’s antibody system will begin to clear out the virus, but, unfortunately, sometimes it is too little too late.
Here is a description of one of the studies you linked which purports to show that HCQ is ineffective.
“The researchers sent either hydroxychloroquine or a placebo by mail to 821 people who had been in close contact with a COVID-19 patient for more than 10 minutes without proper protection. They reported in The New England Journal of Medicine that 12% of the people who took the drug went on to develop COVID-19 symptoms, versus 14% in a placebo group, a difference that was not statistically significant.”
Any idea what happened before the HCQ was delivered in the mail? Is it surprising that those who received HCQ still had COVID-19 infection just like those who didn’t?
Duwayne, Long story short I have a 13 year old son who is a stage four Kidney cancer survivor. His case was particularly grim as the tumor extended from his kidney through his Inferior Vena Cava and into the right ventricle of his heart. It took a team of some of the best Heart Surgeons, Oncologists, General Surgeons and Renal specialists the Texas Medical Center has to offer working together to first shrink the tumor via chemotherapy and then remove it in a marathon 15 hour open heart surgery.
When my 10 year old daughter tested positive for Covid several weeks ago we were obviously concerned about our son so we contacted the doctors involved with his treatment. One of the questions we asked was about hydroxychloroquine, zinc and azithromycin. Their answers were all the same. There is a lack of evidence that it is effective with Covid and they did not believe it would be beneficial and possibly harmful.
Now I am not a Dr. But because of the above scenario I just described I am in contact with some of the best in those fields. When they talk, I listen. It is a formula that has worked through some of the gravest nights any parent should have to endure. I have no reason to doubt their words or advice. I simply fail to believe there is conspiracy to sweep a treatment for this virus under the rug.
Perhaps some of the clinical trials will show promise. Maybe they won't. But one thing is for sure, the conspiracy theory will continue.
That's a great story about your son.
My comment was not aimed at whether your son or anyone else should use HCQ or whether your doctors are experts on HCQ. I question whether the test you linked actually showed HCQ was inneffective in stopping COVID-19 replication.
The US 7-Day average Spread Rate peaked on June 29 at 15.6% and has since slowly declined to 14.0%. This indicates a deceleration in the rate of new cases but still growing. The Spread Rate needs to fall below 12.5% before a declining trend in new cases is indicated.
Meanwhile the declining death rate has reversed as one might expect with the uptick in hospitalizations. Reported deaths are usually highest on Thursdays and Fridays and it would not be surprising to see 1,000 deaths today and/or tomorrow and/or next Thursday or Friday.
If the current trends continue, we could be a couple of weeks away from a drop in the 7-Day average of new cases and and possibly a month away from a decline in the 7-Day average of deaths.
As predicted above, the US new cases peaked after 2 weeks and now, 4 weeks later deaths are peaking as well.
The daily cases peaked at a 7-day average of 69,000 per day and now after 2 weeks the rate is down to 57,000 per day.
The current 7-day average Spread Rate is 11.2% which is well below the "breakeven" rate of 12.5%. This indicates more decline is ahead.
If the current Spread Rate held through year-end, the daily cases would be down to 2,000. Any ideas on what happens when schools restart and restrictions are eased?
Will there be a vaccine available later this year?
Well no vaccine at years end in production or in scale. Me thinks.
The problem hinges around the herd immunity percentage if only 20% then a vaccine is hard to make work, who gets it and for what impact.
HCQ as a vaccine alternative is also a real option if the 20% number is real and the Covid strength decays as expected further.
UK is settling into what appears like herd immunity threshold, good microcosm. Naut will be pleased to discus the virtue of being a lab rat.
opening for Ratty the Australian wing of the red part of all our school maps.
It is unreported in the media but Trump started the vaccine 'warp speed' project in February when people were still shouting at him for not allowing flights from China and Europe. Full scale production has already been initiated on the 3 most promising vaccine candidates in 3rd level testing (large scale human trials) already with the US government picking up the tab for any that fail. The US Army logistics and USAF airlift capacity is already geared up to take distribute the vaccine to points of use and may do that in advance. Effectively, Trump has told them that as soon as the 2nd stage testing - works as expected to create antibodies - is passed then the next stages are all overlaid with the risk being paid for by government. It is entirely possible that a vaccine could be available in October although the medical talking heads are all saying spring 2021 at the earliest, I have decided that even the friendly ones literally cannot be trusted.
I agree that herd immunity is close to being reached but that is because the majority of the world population are/were immune provided they did not have any dietary insufficiency mainly vitamin D and zinc. Asian genotypes have more ACE2 receptors so they really need more vitamin D and zinc but in China the diet is deficient in both so the Chinese population is far more susceptible to a Corona Virus with that uses the ACE2 receptor as its spike protein cellular entry point. ( read these abstracts this from Wuhan pubmed.ncbi.nlm.nih.gov/24172901/#affiliation-1 and this from University of North Carolina Chapel Hill www.ncbi.nlm.nih.gov/pmc/articles/PMC4797993/ note that the teams both include 'bat lady' Zhengli-Li Shi. Also for the curious (like me) see the 'similar articles' and citations links or table of the papers ) The Asian susceptibility may be the reason for the research. It may also be that patient zero was Asian with a poor diet so got infected more easily from a minor flaw in bio-safety in the Wuhan lab than a researcher with another genotype would have been.
Duwayne is correctly pointing out the current pandemic 'second wave' seems to have crested. It was probably caused by letting the last of the susceptibles out of lock down be infected or in the southern states having them cluster in air conditioning. You can tell that the crest has passed in another way - the media now emphasize the total number of corona virus infections/deaths and the daily rates which are now less worrisome are below the fold. IT will be a close run between the COVID-19 petering to a halt and the arrival of the vaccine. The vaccine producers ideally would like to have it being distributed/used now so they could claim the drop off in cases was due to vaccinations. I think they will be just too late which is why there are so many talking head puppets saying that we will always be 'living with the virus'.
"Last week, there was a hysterical story in the New York Times about how hundreds of children had become infected at a summer camp in Georgia. It led to crazy, paranoid “guidance” being written by bedwetting journalists, such as this piece for the NPR website advising parents to “look for” things like “consistent, mandatory mask usage for kids and adults” and “6 feet between desks, small class sizes and cohorts”.
As Gummi Bear said on Twitter: “Nobody said children don’t get COVID-19 so not sure what the breaking news is. A 12 year-old child has a 1 in 55,000 chance of dying IF they get it. That same child is 25x more likely to die from other causes. As a society, we have lost all commonsense in terms of risk assessment.”
The above IFR data from the huge seroprevalence survey in Spain – and which almost certainly overstates the IFR in every age category – says children under the age of 10 have an IFR of 0.0029% and those aged 10-18 0.0018%."
so that projection sounds a little pessimistic. 5000??
am I missing something here
And of those 1,600, we can be quite sure a lot of them didn't actually die of Covid-19.
But you're not missing anything. There's a crisis, and our Glorious Leader (the Governor, of course, not that bad-man-Trump) is taking decisive action, so we're re-electing him (in all seriousness - early polling results from the "top 2" style primary showed him with over 50% of the vote).
Meanwhile there's no media attention worth mentioning on Biden, which is the best possible campaign strategy for him.
And even though Trump was actually taking reasonable steps (if inadequate against a real pandemic) back when people were calling him racist for doing so, he's firmly linked in the MSM as responsible for all the Covid-19 deaths. Proving the MSM is quite capable of completely inverting an issue given enough time and manipulated data.
Everything is going just fine, so those who it is going fine for are doubling down on their bet. Maybe they can get Biden in the White House *and* a supermajority in Congress? Doesn't take a lot of mail-in ballots getting "mishandled" to flip an election in some districts.
"Facilitating Zinc Entry Into Cells Is a Crucial Component
Importantly, zinc alone is not capable of fully stopping viral replication, Sardi notes. The reason for this is because zinc is largely insoluble and cannot easily enter through the fatty wall of your cells. Getting all the way into the cell is crucial, as this is where the viral replication occurs.
“[This] makes the discovery of an ionophore as important as zinc’s primary role in infection control,” Sardi points out, adding, “Such a discovery, if put into practice, would have upset the reigning vaccine paradigm that now predominates in modern medicine. Research dollars would evaporate as a cure for seasonal influenza and coronaviruses … would have been found.”
Other Natural Zinc Transporters — Quercetin and EGCG
The good news is drugs like chloroquine and hydroxychloroquine probably would not be necessary either (except for perhaps the most serious cases), as other natural compounds can do the same job.
A comparative study11 published in 2014 looked at two zinc ionophores: quercetin and epigallocatechin-gallate (EGCG found in green tea), noting many of the biological actions of these compounds may in fact be related to their ability to increase cellular zinc uptake. As explained by the authors:
“Labile zinc, a tiny fraction of total intracellular zinc that is loosely bound to proteins and easily interchangeable, modulates the activity of numerous signaling and metabolic pathways. Dietary plant polyphenols such as the flavonoids quercetin (QCT) and epigallocatechin-gallate act as antioxidants and as signaling molecules.
Remarkably, the activities of numerous enzymes that are targeted by polyphenols are dependent on zinc. We have previously shown that these polyphenols chelate zinc cations and hypothesized that these flavonoids might be also acting as zinc ionophores, transporting zinc cations through the plasma membrane.
To prove this hypothesis, herein, we have demonstrated the capacity of QCT and epigallocatechin-gallate to rapidly increase labile zinc in mouse hepatocarcinoma Hepa 1-6 cells as well as, for the first time, in liposomes … The ionophore activity of dietary polyphenols may underlay the raising of labile zinc levels triggered in cells by polyphenols and thus many of their biological actions.”"
Not to play "My Dr. is better than your Dr.," but my opinion on the HCQ and Z-Pak:
I have high school friends who are doctors, and actually one of the students in the youth group I taught in Tulsa are doctors. They are all friends on Facebook that I keep up with. All of them have addressed the practice of off label prescriptions with me which is the practice of prescribing a medication for a purpose other than what it has been FDA approved for. The practice is actually protected because of the recognition that science moves faster than government and regulation.
I actually take an off label prescription to address intestinal issues that arose after my gall bladder was removed. It fixes my issue.
The more mature doctors from among this friends group actually discussed HCQ and Z-pak with me when I requested they do so, and one of them actually addressed it publicly on Facebook. The ones that discussed it with me said they have prescribed this combination for coronavirus, and they all said (although anecdotal) that their experience showed it to be helpful. One of these physicians is actually married to another of our classmates who is currently afflicted with multiple sclerosis. She is actually treated with an off-label chemo that has kept her MS under control for a couple of decades.
One of these actually took the discussion to Facebook, and the public display of vitriol that immediately ensued even caught me by surprise. Why? If someone is helped by such a treatment, why does it disturb the people spewing venom? I don't get this.
I don't normally buy into conspiracy theories, but when have we ever seen a state pharmaceutical board do like Ohio's attempted? Attempting to overrule the doctor and prohibit dispensing HCQ for the treatment of coronavirus? I asked the physicians in my friends list, and they were all irate about this. My cousin who is a pharmacist was dumbfounded, and the other pharmacist in my friends list (the sister of the doctor who was formerly in the youth group I taught) just declined to even try to explain it.
I can understand a scientific discussion, but I don't understand the vitriol and the illogical actions of pharmacy boards unless that is precipitated from the same kind of vitriol I saw in response to my friend.
As for me, if I was diagnosed with coronavirus - a disease that we say has no treatment and is possibly fatal - I would request this off label treatment from my doctor, and if my doctor declined, I would find another doctor (I don't think my PCP would have a problem with it). If I had to go elsewhere to get it, I would. I would do the same with a family member. A little hope is better than none. This is me, though, making a decision about my health and my body. I'm not going to require anybody else do what I would do. I don't understand why those who oppose it would want to tell me why I must comply with what they would do.
EDIT: And on the vaccine: when it is available, I will take it.